New publication: A software package to analyze single-molecule TIRF data

Congratulations to Samson Condon for the publication of his latest paper in Methods!

Sam collaborated with Aaron Hoskins’ group and helped develop the software package AGATHA (A GATHering of Analyses) which is used to facilitate single-molecule TIRF microscopy analyses, including fitting photobleaching traces to a step function.

Kaur H, Jamalidinan F, Condon SGF, Senes A, Hoskins AA “Analysis of spliceosome dynamics by maximum likelihood fitting of dwell time distributions” Methods (2019) 153, 13-21 [PDF]